If you are flying, Lansing's Capital Region International Airport (LAN) (https://www.flylansing.com) is 12 miles from MSU. Free hotel shuttles may be available. Uber, Lyft, and taxi service make it easy to get from LAN to MSU.
A larger airport is Detroit Metropolitan Airport (DTW). This may be the most inexpensive. It is 85 miles from DTW to East Lansing. This does make traditional ride services more costly but the Michigan Flyer (https://www.michiganflyer.com/) is a very good option since it makes a regular loop between DTW, Ann Arbor and East lansing. Check out the schedules and make a reservation (https://www.michiganflyer.com/ScheduleRoute.aspx). While the ride is 2 hours to East Lansing (30 minutes to Ann Arbor), it has WIFI, and is rarely crowded.
If you are driving, we don't need to tell you about GPS (the venue address is next to many of the listed hotels - Old Hort, 506 E Circle, East Lansing, MI 48824). Parking is easy and affordable in East Lansing (https://www.cityofeastlansing.com/ParkingDowntown/) and also check with your hotel.
From Traverse City or Points North via I-75: Proceed south on I-75 to US-127 near Grayling. Proceed south on US-127 to East Lansing. Take the Trowbridge Road exit. Follow Trowbridge Road east to Michigan State University.
From Detroit or Points East via I-96: Proceed west on I-96 to northbound US-127; follow US-127 north to East Lansing. Take the Trowbridge Road exit. Follow Trowbridge Road east to Michigan State University.
From Grand Rapids or Points West via I-96: Proceed east on I-96 to eastbound I-69. Proceed east on I-69 to southbound US-127. Take US-127 south to East Lansing. Take the Trowbridge Road exit. Follow Trowbridge Road east to Michigan State University.
From Flint or Points East via I-69: Proceed southwest on I-69 to southbound US-127. Take US-127 south to East Lansing. Take the Trowbridge Road exit.
From Kalamazoo or Points South via I-69: Proceed east on I-94 to northbound I-69. Take I-69 north to Lansing. Take I-496 east to the Trowbridge Road exit. Follow Trowbridge Road east to Michigan State University.
From Jackson or Points South via US-127: Proceed north on US-127 to East Lansing. Take the Trowbridge Road exit. Follow Trowbridge Road east to Michigan State University.